USB Bypass for YubiKey Fobs Supported by ThinOS?

Hello, 

I am working on a project for my company and a vendor for MFA for our users. The majority of our users use YubiKey 5FNC fobs to 2FA into their workstation when they log in. I would like to use their YubiKey's as their form of MFA for our vendor, however, when plugging a YubiKey into a Wyse P25 Thin Client, Dell OptiPlex 3000 Thin Client, or any other thin clients we have the YubiKey is not showing up as a typical flash drive. It does show its LED light up and when I touch it gold NFC ring it does a few actions. My tower is able to see the YubiKey like a typical flash drive, and I am able to adjust settings on the YubiKey. 

Note: My company also used VMWare Horizon to host our VM's 

I wanted to know if Wyse ThinOS supports USB bypass for YubiKey's or if it is an issue with VMWare Horizon?

Any help is appreciated! Thanks!