Networker: client-side dedupe with 3rd party back end storage

Simple question:  Is Networker able to do client-side/host-side deduplication with a third party array?  I.E., no DataDomain or Avamar in the picture - just the NetWorker software?

We are looking at solutions and trying to consider all options.  We want the benefits of deduplication being performed on the host prior to sending across the wire and are hoping to explore this further with NetWorker and our existing choice of back-end storage.

Thanks in advance!