USB ports not working

There are some issue with USB connections in windows 10 and windows 11 over world after June small security and quality updates but starts to affect PC some time later 

Windows 10 update is KB5039211

Windows 11 update is KB5039212

Affects printers, cutters, lasers and other devices connected to USB ports, they just stops working

Or these updates doesn't do anything harmful to you and everything works fine

Somehow it gives wrong drivers to connected devices and trying to reinstall them for your device just says no USB device connected or installs but still nothing works

Uninstalling update and restarting brings everything back to life, but in beginning of week Microsoft released servicing stack update and they are now unremovable and problem stays, need to wait for next general Windows build release or Roll back Windows (this workaround with rollback in most cases didn't do the trick, then only solution is format hard drive and clean windows install) some time earlier  so can delete these small updates and disable windows auto update till release of new build or some other updates

 But may be this is not your case

@Dellusser1400  - Version of Windows? 

If mouse and keyboard still work, try this: 

1. Power PC off and disconnect power adapter from rear of PC
2. Press/hold PC's power button for ~30 sec
3. Reconnect power adapter, boot and test USB ports again

If that doesn't help, try this:

1. At desktop, open a CMD prompt window, Run as administrator
2. At the prompt, type in: DISM.exe /Online /Cleanup-image /Restorehealth and press Enter. Be sure to include a space in front of each / and note any error messages when that's done
3. Assuming no "unfixed" errors in #2, at the CMD prompt, type in: sfc /scannow and press Enter. Be sure to include a space in front of the / and note any errors when that's done
4.  Assuming no "unfixed" errors in #3, reboot PC and test USB ports again

Can you delete the driver from Device Manager and restart so that it's reinstalled and try testing the functionality?