Best Practice for Broadcom 5709 to EqualLogic PS4000E

We're setting up a new vSphere 4.1 cluster environment using Dell R610's that have an embedded quad port NIC and two Broadcom 5709 NIC's. We also have a pair of Dell Poweredge 6224 switches and a EqualLogic PS4000E (with eight 500GB Drives). We're planning to use iSCSI for our vsphere datastores. Can anyone provide some guidance on how to best setup the equipment above from a Disk (RAID) and redundant Networking perspective?

Thanks!